FACTOR XA INHIBITORS AS NOVEL ANTITHROMBOTIC AGENTS - FACTS AND PERSPECTIVES

被引：29

作者：

KAISER, B ^{[1
]}

HAUPTMANN, J ^{[1
]}

机构：

[1] UNIV JENA,FAC MED,CTR VASC BIOL & MED ERFURT,D-99089 ERFURT,GERMANY

来源：

CARDIOVASCULAR DRUG REVIEWS | 1994年 / 12卷 / 03期

关键词：

ANTICOAGULANTS; ANTISTASIN; ANTITHROMBOTICS; FACTOR XA INHIBITORS; TICK ANTICOAGULANT PEPTIDE;

D O I：

10.1111/j.1527-3466.1994.tb00207.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：225 / 236

页数：12

共 46 条

[31]

NUTT E, 1988, J BIOL CHEM, V263, P10162

[32] PURIFICATION AND CHARACTERIZATION OF RECOMBINANT ANTISTASIN - A LEECH-DERIVED INHIBITOR OF COAGULATION FACTOR-XA [J].

NUTT, EM ;

JAIN, D ;

LENNY, AB ;

SCHAFFER, L ;

SIEGL, PK ;

DUNWIDDIE, CT .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1991, 285 (01) :37-44

[33] SPECIFIC FACTOR XA INHIBITION REDUCES RESTENOSIS AFTER BALLOON ANGIOPLASTY OF ATHEROSCLEROTIC FEMORAL ARTERIES IN RABBITS [J].

RAGOSTA, M ;

GIMPLE, LW ;

GERTZ, SD ;

DUNWIDDIE, CT ;

VLASUK, GP ;

HABER, HL ;

POWERS, ER ;

ROBERTS, WC ;

SAREMBOCK, IJ .

CIRCULATION, 1994, 89 (03) :1262-1271

[34]

SARDANA M, 1991, J BIOL CHEM, V266, P13560

[35] ANTITHROMBOTIC EFFICACY OF RECOMBINANT TICK ANTICOAGULANT PEPTIDE - A POTENT INHIBITOR OF COAGULATION FACTOR-XA IN A PRIMATE MODEL OF ARTERIAL THROMBOSIS [J].

SCHAFFER, LW ;

DAVIDSON, JT ;

VLASUK, GP ;

SIEGL, PKS .

CIRCULATION, 1991, 84 (04) :1741-1748

[36]

SCHAFFER LW, 1991, ARTERIOSCLER THROMB, V12, P879

[37] CRYSTALLIZATION AND PRELIMINARY CRYSTALLOGRAPHIC ANALYSIS OF ANTISTASIN, A LEECH-DERIVED INHIBITOR OF BLOOD-COAGULATION FACTOR-XA [J].

SCHREUDER, H ;

ARKEMA, A ;

DEBOER, B ;

KALK, K ;

DIJKEMA, R ;

MULDERS, J ;

THEUNISSEN, H ;

HOL, W .

JOURNAL OF MOLECULAR BIOLOGY, 1993, 231 (04) :1137-1138

[38] CONJUNCTIVE ENHANCEMENT OF ENZYMATIC THROMBOLYSIS AND PREVENTION OF THROMBOTIC REOCCLUSION WITH THE SELECTIVE FACTOR-XA INHIBITOR, TICK ANTICOAGULANT PEPTIDE - COMPARISON TO HIRUDIN AND HEPARIN IN A CANINE MODEL OF ACUTE CORONARY-ARTERY THROMBOSIS [J].

SITKO, GR ;

RAMJIT, DR ;

STABILITO, II ;

LEHMAN, D ;

LYNCH, JJ ;

VLASUK, GP .

CIRCULATION, 1992, 85 (02) :805-815

[39] SYNTHETIC INHIBITORS OF BOVINE FACTOR-XA AND THROMBIN COMPARISON OF THEIR ANTICOAGULANT EFFICIENCY [J].

STURZEBECHER, J ;

STURZEBECHER, U ;

VIEWEG, H ;

WAGNER, G ;

HAUPTMANN, J ;

MARKWARDT, F .

THROMBOSIS RESEARCH, 1989, 54 (03) :245-252

[40] SYNTHETIC LOW-MOLECULAR-WEIGHT THROMBIN INHIBITORS - MOLECULAR DESIGN AND PHARMACOLOGICAL PROFILE [J].

TAPPARELLI, C ;

METTERNICH, R ;

EHRHARDT, C ;

COOK, NS .

TRENDS IN PHARMACOLOGICAL SCIENCES, 1993, 14 (10) :366-376

← 1 2 3 4 5 →