INTEGRATED HUMAN GENOME-WIDE MAPS CONSTRUCTED USING THE CEPH REFERENCE PANEL

被引：225

作者：

BUETOW, KH

WEBER, JL

LUDWIGSEN, S

SCHERPBIERHEDDEMA, T

DUYK, GM

SHEFFIELD, VC

WANG, ZY

MURRAY, JC

机构：

[1] MARSHFIELD MED RES FDN,CTR MED GENET,MARSHFIELD,WI 54449

[2] HARVARD UNIV,SCH MED,HOWARD HUGHES MED INST,DEPT GENET,BOSTON,MA 02115

[3] UNIV IOWA,DEPT PEDIAT,IOWA CITY,IA 52242

来源：

NATURE GENETICS | 1994年 / 6卷 / 04期

关键词：

D O I：

10.1038/ng0494-391

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

High resolution linkage maps have proven to be invaluable tools in genetic investigations. We have assembled a collection of genetic maps constructed from primary data collected from investigators performing genotyping using the Centre Etude Polymorphism Humain (CEPH) reference pedigree panel. These maps were constructed using a rigorous, semi-automated map construction algorithm that evaluates the integrity of the maps during construction. Two classes of maps were produced: a high confidence ''skeletal'' set composed of 544 PCR based markers, and a more highly annotated ''framework'' set containing maps of 1,123 markers. Genetic map locations within the framework maps are provided for an additional 1,758 loci without statistically unique interval assignments.

引用

页码：391 / 393

页数：3

共 9 条

[1]

BUETOW KH, 1991, AM J HUM GENET, V49, P985

[2] PROGRAM DESCRIPTION - CENTER-DETUDE-DU-POLYMORPHISME-HUMAIN (CEPH) - COLLABORATIVE GENETIC-MAPPING OF THE HUMAN GENOME [J].

DAUSSET, J ;

CANN, H ;

COHEN, D ;

LATHROP, M ;

LALOUEL, JM ;

WHITE, R .

GENOMICS, 1990, 6 (03) :575-577

[3] A GENETIC-LINKAGE MAP OF THE HUMAN GENOME [J].

DONISKELLER, H ;

GREEN, P ;

HELMS, C ;

CARTINHOUR, S ;

WEIFFENBACH, B ;

STEPHENS, K ;

KEITH, TP ;

BOWDEN, DW ;

SMITH, DR ;

LANDER, ES ;

BOTSTEIN, D ;

AKOTS, G ;

REDIKER, KS ;

GRAVIUS, T ;

BROWN, VA ;

RISING, MB ;

PARKER, C ;

POWERS, JA ;

WATT, DE ;

KAUFFMAN, ER ;

BRICKER, A ;

PHIPPS, P ;

MULLERKAHLE, H ;

FULTON, TR ;

NG, S ;

SCHUMM, JW ;

BRAMAN, JC ;

KNOWLTON, RG ;

BARKER, DF ;

CROOKS, SM ;

LINCOLN, SE ;

DALY, MJ ;

ABRAHAMSON, J .

CELL, 1987, 51 (02) :319-337

[4] THE CEPH1 CONSORTIUM LINKAGE MAP OF HUMAN CHROMOSOME-1 [J].

DRACOPOLI, NC ;

OCONNELL, P ;

ELSNER, TI ;

LALOUEL, JM ;

WHITE, RL ;

BUETOW, KH ;

NISHIMURA, DY ;

MURRAY, JC ;

HELMS, C ;

MISHRA, SK ;

DONISKELLER, H ;

HALL, JM ;

LEE, MK ;

KING, MC ;

ATTWOOD, J ;

MORTON, NE ;

ROBSON, EB ;

MAHTANI, M ;

WILLARD, HF ;

ROYLE, NJ ;

PATEL, I ;

JEFFREYS, AJ ;

VERGA, V ;

JENKINS, T ;

WEBER, JL ;

MITCHELL, AL ;

BALE, AE .

GENOMICS, 1991, 9 (04) :686-700

[5]

H/CEPH Collaborative Mapping Group, 1992, SCIENCE, V258, P67

[6]

KEATS BJB, 1981, LINKAGE CHROMOSOME M

[7]

MORTON NE, 1955, AM J HUM GENET, V7, P277

[8] A 2ND-GENERATION LINKAGE MAP OF THE HUMAN GENOME [J].

WEISSENBACH, J ;

GYAPAY, G ;

DIB, C ;

VIGNAL, A ;

MORISSETTE, J ;

MILLASSEAU, P ;

VAYSSEIX, G ;

LATHROP, M .

NATURE, 1992, 359 (6398) :794-801

[9] THE CEPH CONSORTIUM PRIMARY LINKAGE MAP OF HUMAN CHROMOSOME-10 [J].

WHITE, RL ;

LALOUEL, JM ;

NAKAMURA, Y ;

DONISKELLER, H ;

GREEN, P ;

BOWDEN, DW ;

MATHEW, CGP ;

EASTON, DF ;

ROBSON, EB ;

MORTON, NE ;

GUSELLA, JF ;

HAINES, JL ;

RETIEF, AE ;

KIDD, KK ;

MURRAY, JC ;

LATHROP, GM ;

CANN, HM .

GENOMICS, 1990, 6 (03) :393-412

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