MECHANISMS OF SLEEP CONTROL

被引:43
作者
SIEGEL, JM
机构
[1] Neurobiology Research, Sepulveda Veterans Administration Medical Center, Sepulveda, CA
[2] Department of Psychiatry and Brain Research Institute, UCLA Medical Center, Los Angeles, CA
关键词
Acetylcholine; Basal forebrain; Locus ceruleus; Non-rapid-eye-movement sleep; Norepinephrine; Nucleus solitarius; Raphe; Rapid-eye-movement sleep;
D O I
10.1097/00004691-199001000-00005
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Neurons in the dorsolateral pontine reticular formation, in interaction with other brainstem and forebrain regions, generate the basic phenomena of rapid-eye-movement (REM) sleep. Non-REM sleep is the product of multiple control mechanisms in the forebrain and brainstem. Despite considerable progress in the identification of generation mechanisms, the functions of sleep remain a mystery. I hypothesize that REM sleep has a role in the regulation of receptor sensitivity in the central and peripheral nervous systems. © 1990 American Electroencephalographic Society.
引用
收藏
页码:49 / 65
页数:17
相关论文
共 110 条
[61]  
Morrison A.R., Bowker R.M., The biological significance of PGO spikes in the sleeping cat, Acta Neurobiol Exp, 35, pp. 821-840, (1975)
[62]  
Nauta W.J.H., Hypothalamic regulation of sleep in rats: An experimental study, J Neurophysiol, 9, pp. 285-316, (1946)
[63]  
Orem J., Neuronal mechanisms of respiration in REM sleep, Sleep, 3, pp. 251-267, (1980)
[64]  
Pare D., Smith Y., Parent A., Steriade M., Projections of brainstem core cholinergic and non-cholinergic neurons of cat to intralaminar and reticular thalamic nuclei, Exp Brain Res, 70, pp. 166-180, (1988)
[65]  
Parmeggiani P.L., Thermoregulation during sleep from the viewpoint of homeostasis, Clinical physiology of sleep, pp. 159-169, (1988)
[66]  
Phillipson E.A., Control of breathing during sleep, Am Rev Respr Dis, 118, pp. 909-939, (1978)
[67]  
Pivik R.T., Circar S., Braun C., Nuchal muscle tonus during sleep, wakefulness and tonic immobility in the rabbit, Physiol Behav, 26, pp. 13-20, (1981)
[68]  
Pompeiano O., Hoshino K., Tonic inhibition of dorsal pontine neurons during the postural atonia produced by an anticholinesterase in the decerebrate cat, Arch Ital Biol, 2, pp. 310-340, (1976)
[69]  
Puizillout J.J., Foutz A.S., Characteristics of the experimental reflex sleep induced by vago-aortic nerve stimulation, Electroencephalogr Clin Neurophysiol, 42, pp. 552-563, (1977)
[70]  
Puizillout J.J., Ternaux J.P., Foutz A.S., Fernandez G., Les stades de sommeil de la preparation “encephale isole”: I. Declenchement des pointes ponto-geniculo-occipitales et du sommeil phasique a ondes lentes. Role des noyaux du raphe, Electroencephalogr Clin Neurophysiol, 37, pp. 561-576, (1974)