HYDROXYLAMINE-ALKYNE CYCLIZATIONS - SYNTHESIS OF THE 7-MEMBERED LACTAM STRUCTURE PROPOSED FOR (+/-)-ACACIALACTAM

被引：10

作者：

FOX, ME

HOLMES, AB

FORBES, IT

THOMPSON, M

ZILLER, JW

机构：

[1] UNIV CAMBRIDGE,CHEM LAB,CAMBRIDGE CB2 1EW,ENGLAND

[2] SMITHKLINE BEECHAM PHARMACEUT,HARLOW CM19 5AD,ENGLAND

[3] UNIV CALIF IRVINE,DEPT CHEM,IRVINE,CA 92717

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 48期

关键词：

D O I：

10.1016/S0040-4039(00)60206-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The cyclic nitrone 2 was converted via the key intermediates 7, 12 and 14 into the seven-membered lactam structure 3 proposed for acacialactam. The spectra of the synthetic material differed from that of the natural product for which an alternative structure is tentatively proposed.

引用

收藏

页码：7425 / 7428

页数：4

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