LYMPH-NODE METASTASES IN CARCINOMA OF THE CERVIX UTERI - RESPONSE TO NEOADJUVANT CHEMOTHERAPY AND ITS IMPACT ON SURVIVAL

被引:59
作者
GIAROLI, A
SANANES, C
SARDI, JE
MAYA, AG
BASTARDAS, ML
SNAIDAS, L
RUEDA, NG
VIGHI, S
DIPAOLA, GR
机构
[1] Oncology Department, Buenos Aires University, CP 1120 Buenos Aires
关键词
D O I
10.1016/0090-8258(90)90395-2
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
One hundred and sixty-nine patients with squamous cancer of the cervix uteri treated with three courses of neoadjuvant chemotherapy with the modified VBP scheme are presented. All were subjected to a Wertheim-Meigs operation with paraaortic lymph-adenectomy. The incidence of lymph node metastases is analyzed according to clinical stage, tumor volume, residual tumor in the surgical specimen, and clinical response to neoadjuvant chemotherapy. A significant decrease in the incidence of lymph node involvement was observed in good responders. Survival rates, after 2 years of follow-up, improved in those cases with small residual tumor, negative parametria, and negative nodes. © 1990.
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页码:34 / 39
页数:6
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