FURTHER OBSERVATIONS ON ELECTRICAL PROPERTIES OF HEMOGLOBIN-BOUND WATER

被引：185

作者：

PENNOCK, BE

SCHWAN, HP

机构：

[1] Electromedical Division, Moore School of Electrical Engineering, University of Pennsylvania, Philadelphia

[2] Woman's Medical College, Philadelphia

来源：

JOURNAL OF PHYSICAL CHEMISTRY | 1969年 / 73卷 / 08期

关键词：

D O I：

10.1021/j100842a024

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Solutions of horse hemoglobin of varying concentrations (7.5-26.6 g of Hb/100 cc) were prepared from crystallized Hb. Measurements of the complex dielectric constant of these solutions were made in the frequency range of 1-1200 MHz. This dielectric behavior is described in terms of the dipolar nature of the molecule, the dipolar nature of side chains extending out from the surface, and by a relaxation of a shell of water bound to the surface. The amount of bound water leading to the most reasonable dielectric behavior is 0.2 ± 0.05 g/g of Hb. This bound water is characterized by a change of enthalpy of abou t7 kcal/mol and a characteristic frequency of 500-1000 MHz.

引用

页码：2600 / &

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