LIPASE-CATALYZED TRANSESTERIFICATION OF MESO-CYCLOPENTANE DIOLS

被引：62

作者：

THEIL, F ^{[1
]}

SCHICK, H ^{[1
]}

WINTER, G ^{[1
]}

RECK, G ^{[1
]}

机构：

[1] CENT INST PHYS CHEM,CTR ANALYT,O-1199 BERLIN,GERMANY

来源：

TETRAHEDRON | 1991年 / 47卷 / 36期

关键词：

LIPASE-CATALYZED TRANSESTERIFICATIONS; MESO-CYCLOPENTANE DIOLS; ENANTIOSELECTIVE ACETYLATION; ENZYMES IN ORGANIC SOLVENTS;

D O I：

10.1016/S0040-4020(01)88281-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The lipase-catalyzed transesterification of the meso-cyclopentane diols 1a - 6a with vinyl acetate in tetrahydrofuran/triethylamine in the presence of lipases of different origin has been investigated. Depending on the structure of the substrate and the origin of the lipase chiral cyclopentane derivatives with high enantiomeric excess could be obtained in good to excellent chemical yields.

引用

页码：7569 / 7582

页数：14