CYCLIN-E IS EXPRESSED IN NEURONS AND FORMS COMPLEXES WITH CDK5

被引：61

作者：

MIYAJIMA, M ^{[1
]}

NORNES, HO ^{[1
]}

NEUMAN, T ^{[1
]}

机构：

[1] COLORADO STATE UNIV, DEPT ANAT & NEUROBIOL, FT COLLINS, CO 80523 USA

来源：

NEUROREPORT | 1995年 / 6卷 / 08期

关键词：

CYCLIN E; CDK2; CDK5; CEREBRAL CORTEX; SPINAL CORD; DEVELOPMENT;

D O I：

10.1097/00001756-199505300-00014

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

EXPRESSION Of cyclin dependent kinase cdk5 and its regulator p35 has been shown in the cytoplasm of adult neurons. Here we demonstrate that another potential regulator of cdk5, cyclin E, is expressed in the nervous system and forms complexes with cdk5. Western blot analyses identifies expression of two forms of cyclin E in the mouse nervous system with the 56 kDa form mainly expressed in neurons and 51 kDa form expressed in astrocytes and oligodendrocytes.

引用

页码：1130 / 1132

页数：3

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