FUNCTIONAL EVIDENCE THAT THE PRINCIPAL DNA-REPLICATION ORIGIN OF THE STREPTOMYCES-COELICOLOR CHROMOSOME IS CLOSE TO THE DNAA-GYRB REGION

被引：55

作者：

MUSIALOWSKI, MS

FLETT, F

SCOTT, GB

HOBBS, G

SMITH, CP

OLIVER, SG

机构：

[1] UNIV MANCHESTER,INST SCI & TECHNOL,MANCHESTER BIOTECHNOL CTR,MANCHESTER M60 1QD,LANCS,ENGLAND

[2] UNIV MANCHESTER,INST SCI & TECHNOL,DEPT BIOCHEM & APPL MOLEC BIOL,MANCHESTER M60 1QD,LANCS,ENGLAND

来源：

JOURNAL OF BACTERIOLOGY | 1994年 / 176卷 / 16期

关键词：

D O I：

10.1128/jb.176.16.5123-5125.1994

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The degree of overrepresentation of selected chromosomal genes in rapidly growing cultures of Streptomyces coelicolor was assessed by quantitative DNA hybridization analysis. The results are consistent with the hypothesis that the principal origin of replication is close to the dnaA-gyrB region, in the center of the linear chromosome, and that replication proceeds bidirectionally.

引用

页码：5123 / 5125

页数：3

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