RESERVOIR OF HEPATITIS-B

被引:8
作者
LIM, KS [1 ]
CATTERALL, RD [1 ]
SIMON, R [1 ]
DANE, DS [1 ]
BRIGGS, M [1 ]
TEDDER, RS [1 ]
机构
[1] MIDDLESEX HOSP,SCH MED,DEPT BACTERIOL & VIROL,LONDON W1,ENGLAND
基金
英国惠康基金;
关键词
D O I
10.1016/S0163-4453(79)80009-2
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
A total of 7300 patients attending a clinic for sexually transmitted diseases were screened for hepatitis B surface antigen (HbsAg). The 72 HBsAg positive sera found were tested for 'e' antigen and antibody (HBe and anti-HBe) by immunodiffusion and radioimmunoassay and the patients were followed up to find out whether they were HBsAg carriers or suffering from acute hepatitis B infections. The majority of HBe positive patients were found to be carriers. Seventeen of 19 HBe positive carriers and 14 of 16 patients with acute infections were male homosexuals. Fourteen of 24 (58 per cent) male homosexual carriers from the United Kingdom or other countries with a low prevalence of hepatitis B were HBc positive. The effect of identifying and then treating or counselling HBe positive HBsAg carriers is discussed. © 1979 The British Society for the Study of Infection.
引用
收藏
页码:163 / 170
页数:8
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