A NOVEL DISPLACEMENT ROUTE TO P-CHIRAL PHOSPHINE OXIDES OF HIGH ENANTIOMERIC PURITY

被引：16

作者：

CARDELLICCHIO, C

FIANDANESE, V

NASO, F

PACIFICO, S

KOPROWSKI, M

PIETRUSIEWICZ, KM

机构：

[1] UNIV BARI,DIPARTMENTO CHIM,CTR STUDIO METODOL INNOVAT SINTESI ORGAN,CNR,I-70126 BARI,ITALY

[2] POLISH ACAD SCI,CTR MOLEC & MACROMOLEC STUDIES,PL-90363 LODZ,POLAND

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 34期

关键词：

D O I：

10.1016/S0040-4039(00)73428-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reactions of (R)-(1-chlorovinyl)methylphenylphosphine oxide with aryl and alkenyl Grignard reagents result in highly stereoselective displacement of the halovinyl group and afford virtually enantiomerically pure arylmethylphenyl and alkenylmethylphenylphosphine oxides of inverted configuration at phosphorus.

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收藏

页码：6343 / 6346

页数：4

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