ON THE USE OF HYDROPHOBIC PROBES IN THE CHROMATOGRAPHIC PURIFICATION OF SOLID-PHASE-SYNTHESIZED PEPTIDES

被引：4

作者：

GARCIAECHEVERRIA, C ^{[1
]}

机构：

[1] CIBA GEIGY LTD, CENT RES LABS, CH-4002 BASEL, SWITZERLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1995年 / 07期

关键词：

D O I：

10.1039/c39950000779

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A strategy for the reversed-phase chromatographic purification of solid-phase-synthesized peptides is described and illustrated by the synthesis of a 23-mer model peptide; the target peptide is distinguished from terminated by-products by the attachment of a hydrophobic probe to the resin-bound peptide.

引用

页码：779 / 780

页数：2

共 8 条

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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (16) : 6981 - 6985
[7] FUNAKOSHI S, 1993, PEPTIDE CHEMISTRY 1992, P99
[8] MAGAININS, A CLASS OF ANTIMICROBIAL PEPTIDES FROM XENOPUS SKIN - ISOLATION, CHARACTERIZATION OF 2 ACTIVE FORMS, AND PARTIAL CDNA SEQUENCE OF A PRECURSOR
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