REACTION GAS-CHROMATOGRAPHY IN SEALED GLASS-CAPILLARIES - DEHYDRATION, REDUCTION AND OXIDATION REACTIONS, AND THE SYNTHESIS OF REFERENCE COMPOUNDS

The sealed glass capillary technique of reaction gas chromatography, previously described for hydrogenation, hydrogenolysis and ozonolysis, has been extended to include the dehydration of alcohols to olefins, the reduction of carbonyl groups to primary and secondary alcohols, and the oxidation of alcohols to aldehydes and ketones on the microgram and submicrogram scale. The three new techniques have been coupled with those previously described to form the basis of a very convenient and rapid means of synthesising microgram quantities of compounds required for the measurement of retention and mass spectral data. © 1979.