THE SYNTHESIS AND RESOLUTION OF (+/-)-1,4-DI-O-BENZYL-2,3-O-ISOPROPYLIDENE-MYO-INOSITOL

被引：21

作者：

DESAI, T ^{[1
]}

GIGG, J ^{[1
]}

GIGG, R ^{[1
]}

MARTINZAMORA, E ^{[1
]}

SCHNETZ, N ^{[1
]}

机构：

[1] NATL INST MED RES, LIPID & GEN CHEM LAB, LONDON NW7 1AA, ENGLAND

来源：

CARBOHYDRATE RESEARCH | 1994年 / 258卷

关键词：

D O I：

10.1016/0008-6215(94)84081-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An improved procedure for the preparation of 1,2-O-isopropylidene-myo-inositol is described. Racemic 1,4-di-O-benzyl-2,3-O-isopropylidene-myo-inositol was prepared by tin-mediated benzylation of 1,2-O-isopropylidene-myo-inositol and resolved readily by crystallisation of the omega-camphanates. The use of the chiral 1,4-di-O-benzyl-2,3-O-isopropylidene-myo-inositols as intermediates for the preparation of other chiral derivatives of myo-inositol was investigated.

引用

页码：135 / 144

页数：10

共 19 条

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