SEQUENCE OF THE NUCLEOCAPSID PROTEIN GENE OF MACHUPO VIRUS - CLOSE RELATIONSHIP WITH ANOTHER SOUTH-AMERICAN PATHOGENIC ARENAVIRUS, JUNIN

被引：19

作者：

GRIFFITHS, CM ^{[1
]}

WILSON, SM ^{[1
]}

CLEGG, JCS ^{[1
]}

机构：

[1] PUBL HLTH LAB SERV,CTR APPL MICROBIOL & RES,DIV PATHOL,PORTON DOWN,SALISBURY SP4 0JG,WILTS,ENGLAND

来源：

ARCHIVES OF VIROLOGY | 1992年 / 124卷 / 3-4期

关键词：

D O I：

10.1007/BF01309817

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The sequence of the nucleocapsid (N) protein of Machupo virus (causative agent of Bolivian haemorrhagic fever) has been determined, and used to infer a phylogenetic relationship to other arenaviruses. The relationship of the virus to Junin and Tacaribe viruses, together with previous demonstrations of antigenic similarity and cross-protection by heterologous viruses, suggest that vaccines developed against Argentine haemorrhagic fever might also be effective against the Bolivian disease.

引用

页码：371 / 377

页数：7

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