(+)-EXO-BREVICOMIN VIA AN ORGANOMETALLIC BOULEVARD

被引：16

作者：

SODERQUIST, JA

RANE, AM

机构：

[1] Department of Chemistry, University of Puerto Rico Rio Piedras, Puerto, Rico

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 32期

关键词：

D O I：

10.1016/S0040-4039(00)60668-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The brevicomin carbon skeleton was efficiently constructed through a novel 2 + 3 + 4 sequence via organocuprate and Suzuki couplings. The Sharpless catalytic asymmetric dihydroxylation provided either naturally occurring (+)-exo-brevicomin (+)-7 or its enantiomer, (-)-7, both in 95% ee, in 61% overall yield from allyl bromide.

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收藏

页码：5031 / 5034

页数：4

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