A LINKAGE MAP OF HUMAN-CHROMOSOME-14, INCLUDING 13 GENE LOCI

被引：10

作者：

COX, DW ^{[1
]}

BILLINGSLEY, G ^{[1
]}

NGUYEN, VTT ^{[1
]}

机构：

[1] UNIV TORONTO,DEPT MOLEC & MED GENET,TORONTO,ON,CANADA

来源：

GENOMICS | 1994年 / 23卷 / 02期

关键词：

D O I：

10.1006/geno.1994.1508

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The long arm of human chromosome 14 (14q), an acrocentric chromosome, is estimated to be approximately 93 Mb in length. Genetic maps published to date have included mostly random DNA markers. The map we present here includes 13 genes, as well as 29 random DNA segments, based on typing of the CEPH families. Our map has been placed in context with other published maps. The resulting map of 42 loci has markers on average 5 cM apart and has a total length of 163 cM. The map order differs in the telomeric region from that of other maps previously published. 14q has homology, throughout approximately half its length, with mouse chromosome 12 and has a proximal region of homology with mouse chromosome 14. (C) 1994 Academic Press, Inc.

引用

页码：331 / 337

页数：7

共 35 条

[1] REGIONAL LOCALIZATION OF LOCI ON CHROMOSOME-14 USING SOMATIC-CELL HYBRIDS [J].