STUDIES ON DNA CLEAVING AGENTS - SYNTHESIS AND CHEMICALLY-INDUCED CYCLOAROMATIZATION OF A MONOCYCLIC NEOCARZINOSTATIN CHROMOPHORE ANALOG

被引：36

作者：

WENDER, PA

TEBBE, MJ

机构：

[1] Department of Chemistry, Stanford University, Stanford

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 37期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(00)93481-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of an acyclic analogue of neocarzinostatin chromophore is described. This analogue is found to undergo cycloaromatization in the presence of thiols; the process involves a previously undetected internal hydrogen abstraction reaction.

引用

页码：4863 / 4866

页数：4

共 29 条

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