INVESTIGATIONS OF ARISTEROMYCIN BIOSYNTHESIS - EVIDENCE FOR THE INTERMEDIACY OF A 2-ALPHA,3-ALPHA-DIHYDROXY-4-BETA-(HYDROXYMETHYL)CYCLOPENTANE-1-BETA-AMINE

被引：19

作者：

PARRY, RJ ^{[1
]}

HARIDAS, K ^{[1
]}

DEJONG, R ^{[1
]}

JOHNSON, CR ^{[1
]}

机构：

[1] WAYNE STATE UNIV,DEPT CHEM,DETROIT,MI 48202

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 10期

关键词：

D O I：

10.1039/c39910000740

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Administration of doubly-labelled forms of D-glucose to the fermentation broth of Streptomyces citricolor followed by isotopic trapping has provided evidence for the intermediacy of a 2-alpha,3-alpha-dihydroxy-4-beta-(hydroxymethyl)cyclopentane-1-beta-amine 7 or 8 in the biosynthesis of the nucleoside antibiotic aristeromycin 1.

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页码：740 / 741

页数：2

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