A FACILE SYNTHESIS OF 5-SUBSTITUTED 1-METHYLURACILS AND CYTOSINE

被引:51
作者
SAKAI, TT
POGOLOTTI, AL
SANTI, DV
机构
[1] Department of Chemistry, University of California at Santa Barbara
关键词
D O I
10.1002/jhet.5570050618
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A facile, general synthesis for a number of 5‐substituted‐1‐methyluracils and cytosine which is suitable for the preparation of micro‐quantities is reported. In contrast to other methods, the 5‐substituent plays no role in determining the position of alkylation. 1‐Methyl‐5‐hydroxymethyluracil and 1‐methyl‐5‐formyluracil have also been synthesized by an alternate route. Copyright © 1968 Journal of Heterocyclic Chemistry
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页码:849 / +
页数:1
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