CHROMOSOME MICROTECHNOLOGY - MICRODISSECTION AND MICROCLONING

被引：14

作者：

GREULICH, KO

机构：

[1] K. O. Greulich is at the Physikalisch Chemisches Institut, University of Heidelberg, Heidelberg

来源：

TRENDS IN BIOTECHNOLOGY | 1992年 / 10卷 / 1-2期

关键词：

D O I：

10.1016/0167-7799(92)90168-U

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The physical microdissection of chromosomes and subsequent microcloning of dissected fragments is enabling the generation of very large numbers of cloned unique sequences from defined chromosomal regions. In addition to use in constructing region-specific libraries of the entire human genome and providing probes for mapping and sequencing purposes, such chromosome microtechnology should facilitate the search for disease-associated genes in defined chromosome regions.

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页码：48 / 51

页数：4

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