CONJUGATE ADDITION TO CHIRAL GAMMA-HETEROSUBSTITUTED DELTA-LACTONES AS PIVOTAL SYNTHONS FROM L-GLUTAMIC ACID - SYNTHESIS OF AN OPTICALLY-ACTIVE LIGNAN LACTONE - (-)-HINOKININ

被引：37

作者：

YODA, H ^{[1
]}

NAITO, S ^{[1
]}

TAKABE, K ^{[1
]}

TANAKA, N ^{[1
]}

HOSOYA, K ^{[1
]}

机构：

[1] KYOTO INST TECHNOL,FAC TEXT SCI,KYOTO 606,JAPAN

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 52期

关键词：

D O I：

10.1016/S0040-4039(00)97315-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Asymmetric induction in conjugate addition of new chiral gamma-heterosubstituted-alpha, beta-unsaturated sigma-lactones from L-glutamic acid was accomplished in high diasteroselectivity with the formation of trans-(R,S)-adducts and was disclosed to serve as a versatile procedure for the asymmetric synthesis of antileukemic lignan lactones.

引用

页码：7623 / 7626

页数：4

共 24 条

[21] SELECTIVE SYNTHESIS BY USE OF LEWIS-ACIDS IN THE PRESENCE OF ORGANOCOPPER AND RELATED REAGENTS
YAMAMOTO, Y
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1986, 25 (11): : 947 - 959
[22] SYNTHESES OF ACYCLIC ANALOGS OF KAINOIDS AND NEUROEXCITATORY ACTIVITY
YANAGIDA, M
HASHIMOTO, K
ISHIDA, M
SHINOZAKI, H
SHIRAHAMA, H
[J]. TETRAHEDRON LETTERS, 1989, 30 (29) : 3799 - 3802
[23] YODA H, 1989, CHEM EXPRESS, V4, P585
[24] CHIRALITY TRANSFER DURING CYCLOBUTYL CYCLOPROPYLMETHYL HOMOALLYL CATION REARRANGEMENT AND SYNTHESIS OF (-)-ELDANOLIDE
YOKOYAMA, Y
YUNOKIHARA, M
[J]. CHEMISTRY LETTERS, 1983, (08) : 1245 - 1248

← 1 2 3 →