EVOLUTION OF INFLUENZA-A(H1N1) VIRUSES DURING A PERIOD OF LOW ANTIGENIC DRIFT IN 1986-91 - SEQUENCE OF THE HA1 DOMAIN OF INFLUENZA-A FINLAND 158 91

被引：9

作者：

KINNUNEN, L ^{[1
]}

IKONEN, N ^{[1
]}

POYRY, T ^{[1
]}

PYHALA, R ^{[1
]}

机构：

[1] NATL PUBL HLTH INST,SF-00300 HELSINKI,FINLAND

来源：

RESEARCH IN VIROLOGY | 1992年 / 143卷 / 01期

关键词：

INFLUENZA; HEMAGGLUTININ; NUCLEOTIDE; SEQUENCE COMPARISON; ANTIGENIC DRIFT; EVOLUTION; VACCINES;

D O I：

10.1016/S0923-2516(06)80071-3

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

This study used the nucleotide sequence coding for the HA1 domain of virus haemagglutinin to show that influenza A/Finland/158/91, which represents the H1N1 sub-type viruses prevalent in Finland in 1990/91, was a direct descendant of a virus (A/NN/1605/88) isolated during the 1988/89 epidemic season in Japan. The elevated rate of 7.4 x 10(-3) nucleotide substitutions per site per year is discussed. The new branch of H1N1 subtype viruses is characterized by loss of a glycosylation site, which may affect subsequent antigenic drift.

引用

收藏

页码：11 / 16

页数：6

相关论文

共 16 条

[1] THE ANTIGENIC STRUCTURE OF THE INFLUENZA-VIRUS A/PR/8/34 HEMAGGLUTININ (H-1 SUBTYPE) [J].

CATON, AJ ;

BROWNLEE, GG ;

YEWDELL, JW ;

GERHARD, W .

CELL, 1982, 31 (02) :417-427

[2] NUCLEOTIDE-SEQUENCE OF THE INFLUENZA-VIRUS A/USSR/90/77 HEMAGGLUTININ GENE [J].

CONCANNON, P ;

CUMMINGS, IW ;

SALSER, WA .

JOURNAL OF VIROLOGY, 1984, 49 (01) :276-278

[3] PATHWAYS OF EVOLUTION OF INFLUENZA-A (H1N1) VIRUSES FROM 1977 TO 1986 AS DETERMINED BY OLIGONUCLEOTIDE MAPPING AND SEQUENCING STUDIES [J].

COX, NJ ;

BLACK, RA ;

KENDAL, AP .

JOURNAL OF GENERAL VIROLOGY, 1989, 70 :299-313

[4] POSITIVE DARWINIAN EVOLUTION IN HUMAN INFLUENZA-A VIRUSES [J].

FITCH, WM ;

LEITER, JME ;

LI, XQ ;

PALESE, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (10) :4270-4274

[5] GENETIC-RELATIONSHIP BETWEEN THE HA GENES OF TYPE-A INFLUENZA-VIRUSES ISOLATED IN OFF-SEASONS AND LATER EPIDEMIC SEASONS [J].

NAKAJIMA, S ;

NAKAMURA, K ;

NISHIKAWA, F ;

NAKAJIMA, K .

EPIDEMIOLOGY AND INFECTION, 1991, 106 (02) :383-395

[6] DIRECT ISOLATION IN EGGS OF INFLUENZA-A (H1N1) AND INFLUENZA-B VIRUSES WITH HEMAGGLUTININS OF DIFFERENT ANTIGENIC AND AMINO-ACID-COMPOSITION [J].

OXFORD, JS ;

NEWMAN, R ;

CORCORAN, T ;

BOOTMAN, J ;

MAJOR, D ;

YATES, P ;

ROBERTSON, J ;

SCHILD, GC .

JOURNAL OF GENERAL VIROLOGY, 1991, 72 :185-189

[7] SEQUENCE OF AN INFLUENZA-VIRUS HEMAGGLUTININ DETERMINED DIRECTLY FROM A CLINICAL-SAMPLE [J].

RAJAKUMAR, A ;

SWIERKOSZ, EM ;

SCHULZE, IT .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (11) :4154-4158

[8] THE ANTIGENICITY AND EVOLUTION OF INFLUENZA-H1 HEMAGGLUTININ, FROM 1950-1957 AND 1977-1983 - 2 PATHWAYS FROM ONE GENE [J].

RAYMOND, FL ;

CATON, AJ ;

COX, NJ ;

KENDAL, AP ;

BROWNLEE, GG .

VIROLOGY, 1986, 148 (02) :275-287

[9] ANTIGENICITY AND EVOLUTION AMONGST RECENT INFLUENZA-VIRUSES OF H1N1 SUBTYPE [J].

RAYMOND, FL ;

CATON, AJ ;

COX, NJ ;

KENDAL, AP ;

BROWNLEE, GG .

NUCLEIC ACIDS RESEARCH, 1983, 11 (20) :7191-7203

[10] STRUCTURAL-CHANGES IN THE HEMAGGLUTININ WHICH ACCOMPANY EGG ADAPTATION OF AN INFLUENZA-A(H1N1) VIRUS [J].

ROBERTSON, JS ;

BOOTMAN, JS ;

NEWMAN, R ;

OXFORD, JS ;

DANIELS, RS ;

WEBSTER, RG ;

SCHILD, GC .

VIROLOGY, 1987, 160 (01) :31-37