PREDICTION OF GAS-CHROMATOGRAPHY FLAME IONIZATION DETECTOR RESPONSE FACTORS FROM MOLECULAR-STRUCTURES

被引：246

作者：

JORGENSEN, AD ^{[1
]}

PICEL, KC ^{[1
]}

STAMOUDIS, VC ^{[1
]}

机构：

[1] ARGONNE NATL LAB,DIV SUPPORT SERV,ARGONNE,IL 60439

来源：

ANALYTICAL CHEMISTRY | 1990年 / 62卷 / 07期

关键词：

D O I：

10.1021/ac00206a007

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The prediction of flame ionization detector response factors as a function of molecular structure components is evaluated with modern capillary column gas chromatography equipment that Included an on-column injector. The effect on the standard carbon content based response by electronegative atoms is analyzed for various functional groups. This study updates much earlier work that characterized the decrease In signal response by using average correction factors for each functional group. The effective carbon number concept based on naphthalene as the Internal standard was used. For 56 compounds containing a single functional group, predictions based on these average responses reproduced the actual response to within 1.7 % on average. This model was then extended to bifunctional groups with similar success for several molecules. The effects of changes In temperature programming and concentration were found to be minimal within the range studied. © 1990, American Chemical Society. All rights reserved.

引用

页码：683 / 689

页数：7

共 14 条

[11] CALCULATION OF FLAME IONIZATION DETECTOR RELATIVE RESPONSE FACTORS USING THE EFFECTIVE CARBON NUMBER CONCEPT [J].