EPSTEIN-BARR-VIRUS IN CUTANEOUS LYMPHOMATOID GRANULOMATOSIS

被引：16

作者：

ANGEL, CA

SLATER, DN

ROYDS, JA

NELSON, SNP

BLEEHEN, SS

机构：

[1] ROTHERHAM HOSP NHS TRUST,DEPT HISTOPATHOL,ROTHERHAM,ENGLAND

[2] UNIV SHEFFIELD,DEPT DERMATOL,SHEFFIELD,S YORKSHIRE,ENGLAND

来源：

HISTOPATHOLOGY | 1994年 / 25卷 / 06期

关键词：

EPSTEIN-BARR VIRUS; EBER; LYMPHOMATOID GRANULOMATOSIS; IN SITU HYBRIDIZATION;

D O I：

10.1111/j.1365-2559.1994.tb01373.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Epstein-Barr virus (EBV) has been associated with various extra-cutaneous lymphoproliferative diseases and it has been suggested that EBV may have a similar aetiological role in the skin. In this study, 10 biopsies from 7 cases of primary cutaneous lymphomatoid granulomatosis have been analyzed, using in situ hybridisation, for the presence of EBV encoded RNAs (EBER-1 and EBER-2). Only one case showed positive staining with the EBER probes and it is concluded that, in the skin, the relationship between EBV and lymphomatoid granulomatosis is variable. The role of EBV as an aetiological agent in primary cutaneous lymphomatoid granulomatosis appears less important than in primary respiratory disease.

引用

页码：545 / 548

页数：4

共 18 条

[1] DETECTION OF EPSTEIN-BARR-VIRUS NUCLEIC-ACID SEQUENCES AND PROTEIN IS NODAL T-CELL LYMPHOMAS - RELATION BETWEEN LATENT MEMBRANE PROTEIN-1 POSITIVITY AND CLINICAL COURSE [J].