STEREOSPECIFIC APPROACH TO 3-OXOCEN-7-ONES VIA ALIPHATIC CLAISEN REARRANGEMENT - SYNTHESIS OF (+)-(2R,8S)-LAUTHISAN AND (+)-(2R,8R)-LAUTHISAN

被引：55

作者：

PAQUETTE, LA

SWEENEY, TJ

机构：

[1] Evans Chemical Laboratories, The Ohio State University, Columbus

来源：

TETRAHEDRON | 1990年 / 46卷 / 13-14期

关键词：

D O I：

10.1016/S0040-4020(01)85577-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A general synthetic strategy based upon thermally-induced Claisen ring expansion as the pivotal step allows for rapid elaboration of the lauthisans in enantiomerically pure condition and proper absolute configuration. The short sequence (nine steps) constitutes a new and versatile route to naturally occurring medium-ring ethers. © 1990.

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页码：4487 / 4502

页数：16

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