ALPHA-INTERFERON TREATMENT OF CHRONIC HEPATITIS-C - NEED FOR ACCURATE DIAGNOSIS IN SELECTING PATIENTS

被引：31

作者：

BLACK, M ^{[1
]}

PETERS, M ^{[1
]}

机构：

[1] WASHINGTON UNIV, SCH MED, ST LOUIS, MO 63110 USA

来源：

ANNALS OF INTERNAL MEDICINE | 1992年 / 116卷 / 01期

关键词：

INTERFERON-ALPHA; HEPATITIS-C; AUTOIMMUNE DISEASES; DIAGNOSIS; DIFFERENTIAL; PREDNISONE;

D O I：

10.7326/0003-4819-116-1-86

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Treatment of chronic hepatitis C with alpha-interferon requires careful selection of patients. This process appears relatively straightforward and is usually successful. Occasionally, however, patients are encountered in whom differentiation of chronic hepatitis C from autoimmune chronic active hepatitis is difficult. Because the use of interferon in patients with the latter form of liver disease causes significant exacerbation of indices of injury, precise diagnosis is essential. Such precision could be achieved using tests specific for hepatitis C infection that will soon be introduced.

引用

页码：86 / 88

页数：3

共 8 条

[1] TREATMENT OF CHRONIC HEPATITIS-C WITH RECOMBINANT INTERFERON-ALFA - A MULTICENTER RANDOMIZED, CONTROLLED TRIAL
DAVIS, GL
BALART, LA
SCHIFF, ER
LINDSAY, K
BODENHEIMER, HC
PERRILLO, RP
CAREY, W
JACOBSON, IM
PAYNE, J
DIENSTAG, JL
VANTHIEL, DH
TAMBURRO, C
LEFKOWITCH, J
ALBRECHT, J
MESCHIEVITZ, C
ORTEGO, TJ
GIBAS, A
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1989, 321 (22) : 1501 - 1506
[2] RECOMBINANT INTERFERON-ALFA THERAPY FOR CHRONIC HEPATITIS-C - A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL
DIBISCEGLIE, AM
MARTIN, P
KASSIANIDES, C
LISKERMELMAN, M
MURRAY, L
WAGGONER, J
GOODMAN, Z
BANKS, SM
HOOFNAGLE, JH
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1989, 321 (22) : 1506 - 1510
[3] HEPATITIS-C VIRUS-ANTIBODIES IN CHRONIC ACTIVE HEPATITIS - PATHOGENETIC FACTOR OR FALSE-POSITIVE RESULT
MCFARLANE, IG
SMITH, HM
JOHNSON, PJ
BRAY, GP
VERGANI, D
WILLIAMS, R
[J]. LANCET, 1990, 335 (8692) : 754 - 757
[4] DETECTION OF HEPATITIS-C VIRUS-ANTIBODY IN THE ABSENCE OF VIRAL-RNA IN PATIENTS WITH AUTOIMMUNE HEPATITIS
NISHIGUCHI, S
KUROKI, T
UEDA, T
FUKUDA, K
TAKEDA, T
NAKAJIMA, S
SHIOMI, S
KOBAYASHI, K
OTANI, S
HAYASHI, N
SHIKATA, T
[J]. ANNALS OF INTERNAL MEDICINE, 1992, 116 (01) : 21 - 25
[5] AUTOIMMUNE CHRONIC HEPATITIS EXACERBATED BY ALPHA-INTERFERON
PAPO, T
MARCELLIN, P
BERNUAU, J
DURAND, F
POYNARD, T
BENHAMOU, JP
[J]. ANNALS OF INTERNAL MEDICINE, 1992, 116 (01) : 51 - 53
[6] MECHANISMS OF ACTION OF INTERFERONS
PETERS, M
[J]. SEMINARS IN LIVER DISEASE, 1989, 9 (04) : 235 - 239
[7] AUTOIMMUNE CHRONIC HEPATITIS TYPE-2 MANIFESTED DURING INTERFERON THERAPY IN CHILDREN
RUIZMORENO, M
RUA, MJ
CARRENO, V
QUIROGA, JA
MANNS, M
ZUMBUSCHENFELDE, KHM
[J]. JOURNAL OF HEPATOLOGY, 1991, 12 (02) : 265 - 266
[8] INTERFERON-INDUCED CHRONIC ACTIVE HEPATITIS
SILVA, MO
REDDY, KR
JEFFERS, LJ
HILL, M
SCHIFF, ER
[J]. GASTROENTEROLOGY, 1991, 101 (03) : 840 - 842

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