DOSE CALCULATIONS ABOUT SHIELDED GYNECOLOGICAL COLPOSTATS

被引:56
作者
WILLIAMSON, JF [1 ]
机构
[1] UNIV ARIZONA,DEPT RADIAT ONCOL,TUCSON,AZ 85724
来源
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 1990年 / 19卷 / 01期
关键词
!sup]137[!/sup]Cs; !sup]226[!/sup]Ra; Brachytherapy; Colpostats; Dosimetry; Intracavitary therapy; Monte Carlo;
D O I
10.1016/0360-3016(90)90150-I
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Although shielded gynecological colpostats have been shown experimentally to reduce doses to bladder and rectal tissue by as much as 50%, nearly all previously described dose computation algorithms ignore applicator heterogeneities. We describe the use of realistic Monte Carlo calculations to study the dosimetric effects of applicator structure. Use of sophisticated solid modeling techniques allows the complex internal structure of two commercially-available Fletcher-Suit colpostats, as well as that of 226Ra or 137Cs tubes, to be accurately simulated. Our results show significant differences among these source-applicator combinations. In addition, a novel dose computation algorithm for efficiently estimating absorbed dose near shielded applicators is described. Our approach is based upon empirical separation of primary- and scatter-dose components. The algorithm requires a small base of Monte Carlo-generated data, reproduces the Monte Carlo dose estimates within 3%, and is faster than Monte Carlo by a factor of 15,000. The scatter-separation method has the potential to make accurate dose estimates to bladder, rectum, tumor, and vagina available for clinical treatment planning and for extraction of more meaningful dose-response curves from clinical data. © 1990.
引用
收藏
页码:167 / 178
页数:12
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[11]   DOSIMETRIC COMPARISON OF THE FLETCHER FAMILY OF GYNECOLOGIC COLPOSTATS 1950-1980 [J].
HAAS, JS ;
DEAN, RD ;
MANSFIELD, CM .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1985, 11 (07) :1317-1321
[12]   FLETCHER-SUIT-DELCLOS GYNECOLOGIC APPLICATOR - EVALUATION OF A NEW INSTRUMENT [J].
HAAS, JS ;
DEAN, RD ;
MANSFIELD, CM .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1983, 9 (05) :763-768
[13]   T2 GLOTTIC CANCER - AN ANALYSIS OF DOSE-TIME-VOLUME FACTORS [J].
HARWOOD, AR ;
BEALE, FA ;
CUMMINGS, BJ ;
KEANE, TJ ;
RIDER, WD .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1981, 7 (11) :1501-1505
[14]   CAESIUM-137 SOURCES FOR USE IN INTRACAVITARY AND INTERSTITIAL RADIOTHERAPY [J].
HORSLER, AFC ;
JONES, JC ;
STACEY, AJ .
BRITISH JOURNAL OF RADIOLOGY, 1964, 37 (437) :385-390
[15]  
Hubbell J. H., 1975, Journal of Physical and Chemical Reference Data, V4, P471, DOI 10.1063/1.555523
[16]  
KRISHNASWAMY V, 1972, RADIOLOGY, V155, P181
[17]   CT-ASSISTED ASSESSMENT OF BLADDER AND RECTUM DOSE IN GYNECOLOGICAL IMPLANTS [J].
LING, CC ;
SCHELL, MC ;
WORKING, KR ;
JENTZSCH, K ;
HARISIADIS, L ;
CARABELL, S ;
ROGERS, CC .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1987, 13 (10) :1577-1582
[18]   MEASUREMENT OF DOSE DISTRIBUTION AROUND FLETCHER-SUIT-DELCOS COLPOSTATS USING A THERADOS RADIATION-FIELD ANALYZER (RFA-3) [J].
LING, CC ;
SPIRO, IJ ;
KUBIATOWICZ, DO ;
GERGEN, J ;
PEKSENS, RK ;
BENNETT, JD ;
GAGNON, WF .
MEDICAL PHYSICS, 1984, 11 (03) :326-330
[19]   THE INFLUENCE OF THE NUMBER OF FRACTIONS AND OF OVERALL TREATMENT TIME ON LOCAL-CONTROL AND LATE COMPLICATION RATE IN SQUAMOUS-CELL CARCINOMA OF THE LARYNX [J].
MACIEJEWSKI, B ;
PREUSSBAYER, G ;
TROTT, KR .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1983, 9 (03) :321-328
[20]   SCREENS IN OVOIDS OF A SELECTRON CERVIX APPLICATOR [J].
MEERTENS, H ;
VANDERLAARSE, R .
RADIOTHERAPY AND ONCOLOGY, 1985, 3 (01) :69-80