SELECTIVE REMOVAL OF IMMUNOGLOBULIN-E FROM RAT-BLOOD BY MEMBRANE-IMMOBILIZED ANTIBODY

被引：11

作者：

ADACHI, T ^{[1
]}

MOGI, M ^{[1
]}

HARADA, M ^{[1
]}

KOJIMA, K ^{[1
]}

机构：

[1] MATSUMOTO DENT COLL, DEPT ORAL BIOCHEM, NAGANO 39907, JAPAN

来源：

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | 1995年 / 668卷 / 02期

关键词：

D O I：

10.1016/0378-4347(95)00095-Z

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We examined the suitability of an immunoaffinity membrane [rabbit IgG specific for rat immunoglobulin E (IgE) immobilized on a cellulose membrane] for removing IgE from rat blood passed through a simple extracorporeal circulatory system. To determine the concentration of IgE in the blood, we also developed a highly sensitive chemiluminescence enzyme immunoassay for rat IgE. The IgE levels in the outlet blood from the immunoaffinity membrane module decreased to 30% of the initial concentration within 30 min.

引用

页码：327 / 332

页数：6

共 19 条

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