INFLUENCE OF MAJOR HISTOCOMPATIBILITY HAPLOTYPE ON AUTO-IMMUNE DISEASE VARIES IN DIFFERENT INBRED FAMILIES OF CHICKENS

被引：25

作者：

BACON, LD ^{[1
]}

ROSE, NR ^{[1
]}

机构：

[1] WAYNE STATE UNIV, SCH MED, DEPT IMMUNOL & MICROBIOL, DETROIT, MI 48201 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1979年 / 76卷 / 03期

关键词：

D O I：

10.1073/pnas.76.3.1435

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Three partially inbred substrains of obese strain chickens were studied for the spontaneous development of autoimmune thyroiditis. The influence of the major histocompatibility complex (B haplotype) was marked in 1, less marked but still significant in a 2nd, and barely detectable and transient in a third substrain. These differences in the effect of B haplotype may be due to the overriding action of genes other than those within the B haplotype.

引用

页码：1435 / 1437

页数：3

共 35 条

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