KINETIC RESOLUTION OF RACEMIC ALDEHYDES BY ENANTIOSELECTIVE ALKYLATION

被引：15

作者：

HAYASHI, M ^{[1
]}

MIWATA, H ^{[1
]}

OGUNI, N ^{[1
]}

机构：

[1] YAMAGUCHI UNIV,FAC SCI,DEPT CHEM,YAMAGUCHI 753,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1991年 / 05期

关键词：

D O I：

10.1039/p19910001167

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various types of racemic aldehydes were kinetically resolved by reaction with diethylzinc in the presence of a catalytic amount of a chiral beta-amino alcohol. Kinetic resolution of racemic chloro(phenyl)acetaldehyde gave an optically active form as an unchanged substrate, which could be converted into styrene oxide in high optical purity (97.5% ee).

引用

页码：1167 / 1171

页数：5

共 20 条

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