OPPORTUNITIES FOR NEW CHEMICAL LIBRARIES - UNNATURAL BIOPOLYMERS AND DIVERSOMERS

被引：88

作者：

LISKAMP, RMJ

机构：

[1] Utrecht Institute for Pharmaceutical Sciences Department of Pharmaceutics, Section Organic and Medicinal Chemistry, Utrecht University, Utrecht, 3508 TB

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1994年 / 33卷 / 06期

关键词：

D O I：

10.1002/anie.199406331

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The search for lead compounds may well be simplified by libraries of unnatural compounds, whose lead compounds may require less extensive modifications for the development of drug candidates than those derived from peptide and oligonucleotide libraries. An oligocarbamate library described by Cho et al. and a benzodiazepine library proposed by Hobbs DeWitt et al. should point the way to a large number of libraries. Copyright © 1994 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：633 / 636

页数：4

共 28 条

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