EFFECT OF WATER-MIMICKING ADDITIVES ON THE SYNTHETIC ACTIVITY AND ENANTIOSELECTIVITY IN ORGANIC-SOLVENTS OF A CANDIDA-CYLINDRACEA LIPASE

被引：11

作者：

GUBICZA, L

KELEMENHORVATH, I

机构：

来源：

JOURNAL OF MOLECULAR CATALYSIS | 1993年 / 84卷 / 01期

关键词：

ENANTIOSELECTIVITY; LIPASE; ORGANIC SOLVENT; SYNTHETIC ACTIVITY; WATER-MIMICKING COMPOUNDS;

D O I：

10.1016/0304-5102(93)80080-E

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The activity and enantioselectivity of Candida cylindracea lipase enzyme are affected by a number of solvents. There is a good correlation between the activity and enantioselectivity of the lipase and the log P values of the solvents. Replacement of water with water-mimicking ethylene glycol increased the activity and enantioselectivity of the enzyme. The results show that the dominant factor is the enzyme-water interaction.

引用

页码：L27 / L32

页数：6

共 16 条

[1] ENANTIOMERIC SEPARATION OF 2-CHLOROPROPIONIC ACID BY ENZYMATIC ESTERIFICATION IN ORGANIC-SOLVENTS [J].