EXTRACHROMOSOMAL CIRCULAR RIBOSOMAL DNA IN THE YEAST SACCHAROMYCES CARLSBERGENSIS

被引:28
作者
MEYERINK, JH [1 ]
KLOOTWIJK, J [1 ]
PLANTA, RJ [1 ]
VANDERENDE, A [1 ]
VANBRUGGEN, EFJ [1 ]
机构
[1] UNIV GRONINGEN, BIOCHEM LAB, NL-9747 AG GRONINGEN, NETHERLANDS
关键词
D O I
10.1093/nar/7.1.69
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Purified ribosomal DNA from Saccharomyces carlsbergensis contains a small proportion of circular DNA molecules with a contour length of 3 um or integral multiples thereof. Hybridization of yeast ribosomal DNA with 26 S rRNA, using the R-loop technique, reveals that these circular molecules contain sequences complementary to yeast ribosomal RNA. We suggest that these extrachromosomal rRNA genes may be intermediates in the amplification of rRNA genes in yeast. © 1979 Information Retrieval Limited.
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页码:69 / 76
页数:8
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