MR MEASUREMENT OF BLOOD-FLOW IN THE CARDIOVASCULAR-SYSTEM

Methods for measurement of blood flow with MR were devised many years ago but have been used for diagnosis in only the past few years. The two methods of measurement that have been used most extensively are based on the principles of time of flight and phase shift. A number of factors can influence the accuracy of MR measurements of blood flow. In vitro studies using flow phantoms have verified the accuracy of the phase-shift technique for measuring flow velocities exceeding 5 m/sec, which for practical purposes, encompasses the peak flow encountered in cardiovascular disorders. The flow measurements have been used to quantify valvular heart disease, congenital heart disease, pulmonary arterial disease, thoracic aortic disease, and peripheral vascular disease.