NASAL ADMINISTRATION - A TOOL FOR TOMORROWS SYSTEMIC ADMINISTRATION OF DRUGS

被引：22

作者：

DUCHENE, D

PONCHEL, G

机构：

[1] Laboratoire de Physico-chimie, Pharmacotechnie, Biopharmacie

[2] Faculté de Pharmacie, Université de Paris-Sud, 92290, Châtenay, Malabry, Rue Jean Baptiste Clément

来源：

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY | 1993年 / 19卷 / 1-2期

关键词：

D O I：

10.3109/03639049309038763

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

By its anatomy and physiology, due to the great amount of air treated there, the nasal route represents a very interesting possibility for the administration of products degraded in the gastro-intestinal tract or inhibited by the first hepatic pass. The nasal dosage forms most studied are bioadhesive hydrogels and microspheres, especially for the systemic administration of peptides.

引用

页码：101 / 122

页数：22

共 53 条

[31]

MAITANI Y, 1991, INT J PHARM, V69, P21

[32]

MAITANI Y, 1989, INT J PHARM, V49, P23

[33] ANALYSIS OF STRUCTURAL REQUIREMENTS FOR THE ABSORPTION OF DRUGS AND MACROMOLECULES FROM THE NASAL CAVITY [J].