EXTRACELLULAR-SPACE, BLOOD-VOLUME, AND THE EARLY DUMPING SYNDROME AFTER TOTAL GASTRECTOMY

被引:12
作者
MIHOLIC, J
REILMANN, L
MEYER, HJ
KORBER, H
KOTZERKE, J
HECKER, H
机构
[1] KLIN ABDOMINAL & TRANSPLANTAT CHIRURG,NUKL MED & BIOPHYS ABT,HANOVER,GERMANY
[2] HANOVER MED SCH,MAX PLANCK INST BIOMETRIE,W-3000 HANOVER 61,GERMANY
关键词
D O I
10.1016/0016-5085(90)90608-4
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Extracellular space and blood volume were measured using 82Br dilution and 51Cr-tagged erythrocytes in 24 tumor-free patients after total gastrectomy. Eleven of the patients suffered from early dumping. Age, blood volume, and extracellular space were significantly smaller in dumpers (P < 0.05). The dumping score could be predicted by a multiple regression model considering blood volume per lean body mass and extracellular space (r = 0.637; P = 0.0039). Rapid (t 1 2 < 360 seconds) emptying of the gastric substitute, assessed using a 99Tc-labeled solid test meal, was significantly associated with dumping in addition to extracellular space and blood volume (r = 0.876; P = 0.0018). Both rapid emptying and a narrow extracellular space seem to contribute to the early dumping syndrome. © 1990.
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页码:923 / 929
页数:7
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