MECHANISM OF NORADRENALINE-INDUCED HETEROLOGOUS DESENSITIZATION OF ADENYLATE-CYCLASE STIMULATION IN RAT-HEART MUSCLE-CELLS - INCREASE IN THE LEVEL OF INHIBITORY G-PROTEIN ALPHA-SUBUNITS

被引：126

作者：

REITHMANN, C ^{[1
]}

GIERSCHIK, P ^{[1
]}

SIDIROPOULOS, D ^{[1
]}

WERDAN, K ^{[1
]}

JAKOBS, KH ^{[1
]}

机构：

[1] UNIV MUNICH,MED KLIN 1,D-8000 MUNICH 70,FED REP GER

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY-MOLECULAR PHARMACOLOGY SECTION | 1989年 / 172卷 / 03期

关键词：

D O I：

10.1016/0922-4106(89)90051-5

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：211 / 221

页数：11

共 37 条

[1] MECHANISM OF ISOPRENALINE-INDUCED REFRACTORINESS OF THE BETA-ADRENOCEPTOR-ADENYLATE CYCLASE SYSTEM IN CHICK-EMBRYO CARDIAC-CELLS [J].

BOBIK, A ;

CAMPBELL, JH ;

CARSON, V ;

CAMPBELL, GR .

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1981, 3 (03) :541-553

[2]

BOHM M, 1988, EUR HEART J, V9, P844

[3]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[4] FUNCTIONAL MODIFICATION OF THE GUANINE-NUCLEOTIDE REGULATORY PROTEIN AFTER DESENSITIZATION OF TURKEY ERYTHROCYTES BY CATECHOLAMINES [J].

BRIGGS, MM ;

STADEL, JM ;

IYENGAR, R ;

LEFKOWITZ, RJ .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1983, 224 (01) :142-151

[5] BETA-ADRENERGIC FUNCTION IN HEART-MUSCLE DISEASE AND HEART-FAILURE [J].

BRISTOW, MR ;

KANTROWITZ, NE ;

GINSBURG, R ;

FOWLER, MB .

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 1985, 17 :41-52

[6] MECHANISM OF CHOLERA TOXIN ACTION - COVALENT MODIFICATION OF GUANYL NUCLEOTIDE-BINDING PROTEIN OF ADENYLATE-CYCLASE SYSTEM [J].

CASSEL, D ;

PFEUFFER, T .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1978, 75 (06) :2669-2673

[7] EARLY DECREASE IN SECRETIN-STIMULATED, GLUCAGON-STIMULATED, AND ISOPROTERENOL-STIMULATED CARDIAC ADENYLATE-CYCLASE ACTIVITY IN RATS TREATED WITH ISOPROTERENOL [J].

CHATELAIN, P ;

ROBBERECHT, P ;

DENEEF, P ;

CAMUS, JC ;

CHRISTOPHE, J .

BIOCHEMICAL PHARMACOLOGY, 1982, 31 (03) :347-352

[8] THE EFFECTIVENESS OF INOTROPIC AGENTS IN ISOLATED CARDIAC PREPARATIONS FROM THE HUMAN-HEART [J].

ERDMANN, E .

KLINISCHE WOCHENSCHRIFT, 1988, 66 (01) :1-6

[9] INCREASE OF THE 40,000-MOL WT PERTUSSIS TOXIN SUBSTRATE (G-PROTEIN) IN THE FAILING HUMAN-HEART [J].

FELDMAN, AM ;

CATES, AE ;

VEAZEY, WB ;

HERSHBERGER, RE ;

BRISTOW, MR ;

BAUGHMAN, KL ;

BAUMGARTNER, WA ;

VANDOP, C .

JOURNAL OF CLINICAL INVESTIGATION, 1988, 82 (01) :189-197

[10] DEFICIENT PRODUCTION OF CYCLIC-AMP - PHARMACOLOGICAL EVIDENCE OF AN IMPORTANT CAUSE OF CONTRACTILE DYSFUNCTION IN PATIENTS WITH END-STAGE HEART-FAILURE [J].

FELDMAN, MD ;

COPELAS, L ;

GWATHMEY, JK ;

PHILLIPS, P ;

WARREN, SE ;

SCHOEN, FJ ;

GROSSMAN, W ;

MORGAN, JP .

CIRCULATION, 1987, 75 (02) :331-339

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