MAPPING THE DIABETES POLYGENE IDD3 ON MOUSE CHROMOSOME-3 BY USE OF NOVEL CONGENIC STRAINS

被引：36

作者：

LORD, CJ

BOHLANDER, SK

HOPES, EA

MONTAGUE, CT

HILL, NJ

PRINS, JB

RENJILIAN, RJ

PETERSON, LB

WICKER, LS

TODD, JA

DENNY, P

机构：

[1] UNIV OXFORD, WELLCOME TRUST CTR HUMAN GENET, NUFFIELD DEPT SURG, OXFORD OX3 7BN, ENGLAND

[2] UNIV CHICAGO, DEPT MED, HEMATOL ONCOL SECT, CHICAGO, IL 60637 USA

[3] MERCK RES LABS, DEPT CELLULAR & MOLEC PHARMACOL, RAHWAY, NJ 07065 USA

[4] MERCK RES LABS, DEPT AUTOIMMUNE DIS RES, RAHWAY, NJ 07065 USA

来源：

MAMMALIAN GENOME | 1995年 / 6卷 / 09期

基金：

英国惠康基金;

关键词：

D O I：

10.1007/BF00352359

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Development of novel congenic mouse strains has allowed us to better define the location of the diabetogenic locus, Idd3, on Chromosome (Chr) 3. Congenic strains were identified by use of published and newly developed microsatellite markers, their genomes fingerprinted by a rapid, fluorescence-based approach, and their susceptibility to type 1 diabetes evaluated. The maximum interval containing Idd3 is now approximately 4 cM.

引用

页码：563 / 570

页数：8

共 30 条

[1] A METHOD FOR THE RAPID SEQUENCE-INDEPENDENT AMPLIFICATION OF MICRODISSECTED CHROMOSOMAL MATERIAL [J].

BOHLANDER, SK ;

ESPINOSA, R ;

LEBEAU, MM ;

ROWLEY, JD ;

DIAZ, MO .

GENOMICS, 1992, 13 (04) :1322-1324

[2] TOWARDS HIGH-RESOLUTION MAPS OF THE MOUSE AND HUMAN GENOMES - A FACILITY FOR ORDERING MARKERS TO 0.1 CM RESOLUTION [J].

BREEN, M ;

DEAKIN, L ;

MACDONALD, B ;

MILLER, S ;

SIBSON, R ;

TARTTELIN, E ;

AVNER, P ;

BOURGADE, F ;

GUENET, JL ;

MONTAGUTELLI, X ;

POIRIER, C ;

SIMON, D ;

TAILOR, D ;

BISHOP, M ;

KELLY, M ;

RYSAVY, F ;

RASTAN, S ;

NORRIS, D ;

SHEPHERD, D ;

ABBOTT, C ;

PILZ, A ;

HODGE, S ;

JACKSON, I ;

BOYD, Y ;

BLAIR, H ;

MASLEN, G ;

TODD, JA ;

REED, PW ;

STOYE, J ;

ASHWORTH, A ;

MCCARTHY, L ;

COX, R ;

SCHALKWYK, L ;

LEHRACH, H ;

KLOSE, J ;

GANGADHARAN, U ;

BROWN, S .

HUMAN MOLECULAR GENETICS, 1994, 3 (04) :621-627

[3] A GENOME-WIDE SEARCH FOR HUMAN TYPE-1 DIABETES SUSCEPTIBILITY GENES [J].

DAVIES, JL ;

KAWAGUCHI, Y ;

BENNETT, ST ;

COPEMAN, JB ;

CORDELL, HJ ;

PRITCHARD, LE ;

REED, PW ;

GOUGH, SCL ;

JENKINS, SC ;

PALMER, SM ;

BALFOUR, KM ;

ROWE, BR ;

FARRALL, M ;

BARNETT, AH ;

BAIN, SC ;

TODD, JA .

NATURE, 1994, 371 (6493) :130-136

[4]

DIEHL SR, 1990, AM J HUM GENET, V49, P746

[5]

DIETRICH W, 1992, GENETICS, V131, P423

[6] POLYGENIC CONTROL OF AUTOIMMUNE DIABETES IN NONOBESE DIABETIC MICE [J].

GHOSH, S ;

PALMER, SM ;

RODRIGUES, NR ;

CORDELL, HJ ;

HEARNE, CM ;

CORNALL, RJ ;

PRINS, JB ;

MCSHANE, P ;

LATHROP, GM ;

PETERSON, LB ;

WICKER, LS ;

TODD, JA .

NATURE GENETICS, 1993, 4 (04) :404-409

[7] THE NOD MOUSE - RECESSIVE DIABETOGENIC GENE IN THE MAJOR HISTOCOMPATIBILITY COMPLEX [J].

HATTORI, M ;

BUSE, JB ;

JACKSON, RA ;

GLIMCHER, L ;

DORF, ME ;

MINAMI, M ;

MAKINO, S ;

MORIWAKI, K ;

KUZUYA, H ;

IMURA, H ;

STRAUSS, WM ;

SEIDMAN, JG ;

EISENBARTH, GS .

SCIENCE, 1986, 231 (4739) :733-735

[8]

IKEGAMI H, 1993, LESSONS ANIMAL DIABE, V4, P39

[9] THE MURINE AUTOIMMUNE DIABETES MODEL - NOD AND RELATED STRAINS [J].

KIKUTANI, H ;

MAKINO, S .

ADVANCES IN IMMUNOLOGY, 1992, 51 :285-322

[10] NONGENETIC FACTORS CAUSING TYPE-1 DIABETES [J].

LO, SSS ;

TUN, RYM ;

LESLIE, RDG .

DIABETIC MEDICINE, 1991, 8 (07) :609-618

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