THYROLIBERIN (TRH) INCREASES THYMUS-CELL PROLIFERATION IN RATS

被引：21

作者：

PAWLIKOWSKI, M

ZEREKMELEN, G

WINCZYK, K

机构：

[1] Department of Experimental Endocrinology and Hormone Diagnostics, Institute of Endocrinology, Medical Academy of Łódź, 91-425 Łodz

来源：

NEUROPEPTIDES | 1992年 / 23卷 / 03期

关键词：

D O I：

10.1016/0143-4179(92)90123-E

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The effects of thyroliberin (TRH), a TRH-like tripeptide colon mitosis inhibitor (CMI), a somatostatin analog SMS 201-995 and metoclopramide (dopamine receptor antagonist enhancing prolactin secretion) on rat thymus cell proliferation were investigated. The incorporation of bromodeoxyuridine (BrDU) into thymic cell nuclei was used as an index of the proliferation. It was found that TRH, but not other compounds investigated herein, increased the thymus cell proliferation 12 hours after the injection.

引用

页码：199 / 202

页数：4

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