DEGRADATIVE ROUTES TO ELECTROPHILIC CD-SUBSTRUCTURES OF TAXOL

被引：15

作者：

DIGRANDI, MJ

COBURN, CA

ISAACS, RCA

DANISHEFSKY, SJ

机构：

[1] Laboratory of Bio-Organic Chemistry, Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York, New York 10021

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1993年 / 58卷 / 27期

关键词：

D O I：

10.1021/jo00079a017

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various electrophilic derivatives containing the CD-substructure of taxol and bearing suitable appendages for joining to potential A-ring synthons have been prepared. This chemistry points to the stability of the oxetane to a variety of reaction conditions.

引用

页码：7728 / 7731

页数：4

共 23 条

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