QUANTITATIVE STRUCTURE-SELECTIVITY RELATIONSHIPS - COMPARISON OF THE INHIBITION OF ESCHERICHIA-COLI AND BOVINE LIVER DIHYDROFOLATE-REDUCTASE BY 5-(SUBSTITUTED-BENZYL)-2,4-DIAMINOPYRIMIDINES

被引：48

作者：

DIETRICH, SW ^{[1
]}

BLANEY, JM ^{[1
]}

REYNOLDS, MA ^{[1
]}

JOW, PYC ^{[1
]}

HANSCH, C ^{[1
]}

机构：

[1] POMONA COLL,DEPT CHEM,CLAREMONT,CA 91711

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1980年 / 23卷 / 11期

关键词：

D O I：

10.1021/jm00185a011

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1205 / 1212

页数：8

共 30 条

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[9] QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS OF ANTIMALARIAL AND DIHYDROFOLATE-REDUCTASE INHIBITION BY QUINAZOLINES AND 5-SUBSTITUTED BENZYL-2,4-DIAMINOPYRIMIDINES [J].

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[10] AROMATIC SUBSTITUENT CONSTANTS FOR STRUCTURE-ACTIVITY CORRELATIONS [J].

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