MICE DEFICIENT IN GAMMA-DELTA T-CELLS ARE RESISTANT TO LETHAL INFECTION WITH SALMONELLA-CHOLERAESUIS

被引：32

作者：

EMOTO, M

NISHIMURA, H

SAKAI, T

HIROMATSU, K

GOMI, H

ITOHARA, S

YOSHIKAI, Y

机构：

[1] NAGOYA UNIV,SCH MED,DIS MECHANISM & CONTROL RES INST,HOST DEFENSE & GERMFREE LIFE LAB,NAGOYA,AICHI 466,JAPAN

[2] KYOTO UNIV,INST VIRUS RES,KYOTO 60601,JAPAN

来源：

INFECTION AND IMMUNITY | 1995年 / 63卷 / 09期

关键词：

D O I：

10.1128/IAI.63.9.3736-3738.1995

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Mice deficient in gamma delta T cells were resistant to the gram-negative bacteremic sepsis caused by infection with a high dose of Salmonella choleraesuis accompanied by impaired tumor necrosis factor alpha production in vivo and in vitro. gamma delta T cells may play a role in the pathogenesis of lethal infection with S. cholernesuis.

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页码：3736 / 3738

页数：3

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