The Comparative Analysis of Isotope Clearance Curves in Normal and lschemic Brain

被引:12
作者
Rees, J. Esmond [1 ]
Bull, J. W. D. [1 ]
Du Boulay, G. H. [1 ]
Marshall, John [1 ]
Russell, R. W. Ross [1 ]
Symon, Lindsay [1 ]
机构
[1] Natl Hosp Nervous Dis, Inst Neurol, Queen Sq, London WC1N 3BG, England
关键词
cerebral blood flow; strokes; transient ischemic attacks;
D O I
10.1161/01.STR.2.5.444
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The regional cerebral blood flow has been measured by intracarotid (183)Xenon in ten normal subjects, ten with miscellaneous cerebral ischemic lesions, eight with transient ischemic attacks and seven with completed strokes. The data have been examined by the stochastic and two-compartmental methods of analysis and by reference to the slope of the initial two minutes of the clearance curves. In normal unanesthetized normocapnic subjects the correlation between the results obtained by each of these methods is high, in ischemic lesions the correlation is less god. All three methods, however, are liable to miss, or to misrepresent the significance of, disturbances which can be demonstrated when the proportion and rate of perfusion of gray and white matter are separately estimated,
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页码:444 / 451
页数:8
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