HIV PROTEASE - A NOVEL CHEMOTHERAPEUTIC TARGET FOR AIDS

被引：469

作者：

HUFF, JR

机构：

[1] Department of Medicinal Chemistry, Merck Sharp and Dohme Research Laboratories, West Point

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1991年 / 34卷 / 08期

关键词：

D O I：

10.1021/jm00112a001

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：2305 / 2314

页数：10

共 130 条

[1] AN INHIBITOR OF THE PROTEASE BLOCKS MATURATION OF HUMAN AND SIMIAN IMMUNODEFICIENCY VIRUSES AND SPREAD OF INFECTION [J].

ASHORN, P ;

MCQUADE, TJ ;

THAISRIVONGS, S ;

TOMASSELLI, AG ;

TARPLEY, WG ;

MOSS, B .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (19) :7472-7476

[2] ISOLATION OF A T-LYMPHOTROPIC RETROVIRUS FROM A PATIENT AT RISK FOR ACQUIRED IMMUNE-DEFICIENCY SYNDROME (AIDS) [J].

BARRESINOUSSI, F ;

CHERMANN, JC ;

REY, F ;

NUGEYRE, MT ;

CHAMARET, S ;

GRUEST, J ;

DAUGUET, C ;

AXLERBLIN, C ;

VEZINETBRUN, F ;

ROUZIOUX, C ;

ROZENBAUM, W ;

MONTAGNIER, L .

SCIENCE, 1983, 220 (4599) :868-871

[3] N-MYRISTYLATION OF THE HUMAN IMMUNODEFICIENCY VIRUS TYPE-1 GAG POLYPROTEIN PRECURSOR IN SACCHAROMYCES-CEREVISIAE [J].

BATHURST, IC ;

CHESTER, N ;

GIBSON, HL ;

DENNIS, AF ;

STEIMER, KS ;

BARR, PJ .

JOURNAL OF VIROLOGY, 1989, 63 (07) :3176-3179

[4]

BILLICH S, 1988, J BIOL CHEM, V263, P17905

[5] SYNTHETIC NON-PEPTIDE INHIBITORS OF HIV PROTEASE [J].

BLUMENSTEIN, JJ ;

COPELAND, TD ;

OROSZLAN, S ;

MICHEJDA, CJ .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1989, 163 (02) :980-987

[6] ON THE RATIONAL DESIGN OF RENIN INHIBITORS - X-RAY STUDIES OF ASPARTIC PROTEINASES COMPLEXED WITH TRANSITION-STATE ANALOGS [J].

BLUNDELL, TL ;

COOPER, J ;

FOUNDLING, SI ;

JONES, DM ;

ATRASH, B ;

SZELKE, M .

BIOCHEMISTRY, 1987, 26 (18) :5585-5590

[7]

BLUNDELL TL, 1985, ASPARTIC PROTEINASES, P151

[8] 3-DIMENSIONAL STRUCTURE OF THE COMPLEX OF THE RHIZOPUS-CHINENSIS CARBOXYL PROTEINASE AND PEPSTATIN AT 2.5-A RESOLUTION [J].

BOTT, R ;

SUBRAMANIAN, E ;

DAVIES, DR .

BIOCHEMISTRY, 1982, 21 (26) :6956-6962

[9] IMMUNOPATHOGENESIS OF THE ACQUIRED IMMUNODEFICIENCY SYNDROME [J].

BOWEN, DL ;

LANE, HC ;

FAUCI, AS .

ANNALS OF INTERNAL MEDICINE, 1985, 103 (05) :704-709

[10]

BRITCHER SF, UNPUB

← 1 2 3 4 5 6 7 8 9 10 →