FRONTAL AND PARIETAL LOBE DYSFUNCTION IN DEPRESSION - DELAYED ALTERNATION AND TACTILE LEARNING-DEFICITS

被引：31

作者：

FREEDMAN, M

机构：

[1] BAYCREST CTR GERIATR CARE, ROTMAN RES INST, TORONTO, ON, CANADA

[2] MT SINAI HOSP, DEPT MED, DIV NEUROL, TORONTO M5G 1X5, ON, CANADA

[3] UNIV TORONTO, TORONTO, ON, CANADA

来源：

NEUROPSYCHOLOGIA | 1994年 / 32卷 / 08期

关键词：

D O I：

10.1016/0028-3932(94)90050-7

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

To evaluate frontal and parietal lobe involvement in depression, behavioral tests sensitive to damage in these regions were administered to depressed patients over age 50. Delayed alternation (DA), delayed response and object alternation were used to assess dorsolateral frontal and orbitofrontal function. Tactile learning problems (TOL and TRL) assessed parietal lobe integrity. Depressed patients were significantly impaired on DA, TOL and TRL, suggesting spatial memory (DA) and tactile learning deficits. The functional neuroanatomy underlying these deficits may share features with Parkinson's and Alzheimer's diseases.

引用

页码：1015 / 1025

页数：11

共 62 条

[41] EFFECTS OF SMALL FRONTAL LESIONS ON DELAYED ALTERNATION IN MONKEYS [J].