TANGENTIAL FLOW FILTRATION FOR CONTINUOUS CELL RECYCLE CULTURE OF ACIDOGENIC BACTERIA

被引：17

作者：

CRESPO, JPSG ^{[1
]}

XAVIER, AMRB ^{[1
]}

BARRETO, MTO ^{[1
]}

GONCALVES, LMD ^{[1
]}

ALMEIDA, JS ^{[1
]}

CARRONDO, MJT ^{[1
]}

机构：

[1] CTR TECNOL QUIM BIOL,INST BIOL EXPTL TECNOL,P-2780 OEIRAS,PORTUGAL

来源：

CHEMICAL ENGINEERING SCIENCE | 1992年 / 47卷 / 01期

关键词：

D O I：

10.1016/0009-2509(92)80214-W

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

The operation of cell recycle systems by membrane filtration is discussed, stressing the importance of the mutual interaction between the biological and the physical characteristics of the fermentation process. Broth circulation flow rate, dilution rate, and cell bleed rate are identified as being the most important process variables. Their effects on process performance and criteria for its adequate selection are analysed. Fermentation results for different acidogenic microorganisms are presented and the kinetic modelling of high cell density recycling systems is discussed.

引用

页码：205 / 214

页数：10

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