CONCOMITANT SUBSTRATE AND PRODUCT INHIBITION-KINETICS IN LACTIC-ACID PRODUCTION

被引：71

作者：

GONCALVES, LMD

XAVIER, AMRB

ALMEIDA, JS

CARRONDO, MJT

机构：

[1] UNIV NOVA LISBOA, FAC CIENCIAS & TECHNOL, QUINTA TORRE, 2825 MONTE CAPARICA, LISBON, PORTUGAL

[2] INST BIOL EXP TECN, CTR TECHNOL QUIM & BIOL, OEIRAS, PORTUGAL

来源：

ENZYME AND MICROBIAL TECHNOLOGY | 1991年 / 13卷 / 04期

关键词：

LACTIC ACID; KINETIC MODEL; PRODUCT INHIBITION; SUBSTRATE INHIBITION;

D O I：

10.1016/0141-0229(91)90150-9

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The influence of glucose inhibition on growth and lactic acid production kinetics of Lactobacillus delbrueckii NRRL B445 was studied in batch cultures. Continuous experiments (CSTR) were also carried out. A model for substrate consumption, cell growth, and lactic acid production considering both substrate and product inhibition is proposed; this model fits experimental data better than previously described models, since these have only considered low substrate concentrations. The kinetics of continuous culture can be also described adequately by the model developed from the batch tests.

引用

页码：314 / 319

页数：6

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