ANTIPLATELET CONSTITUENTS OF FORMOSAN RUBIA AKANE

被引：65

作者：

CHUNG, MI

JOU, SJ

CHENG, TH

LIN, CN

KO, FN

TENG, CM

机构：

[1] KAOHSIUNG MED COLL,NAT PROD RES CTR,KAOHSIUNG 807,TAIWAN

[2] NATL TAIWAN UNIV,COLL MED,INST PHARMACOL,TAIPEI 100,TAIWAN

来源：

JOURNAL OF NATURAL PRODUCTS | 1994年 / 57卷 / 02期

关键词：

D O I：

10.1021/np50104a020

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A known steroid, in addition to triterpenoids, anthraquinones, naphthalenes and a new anthraquinone glycoside, xanthopurpurin 3-O-beta-D-glucoside, were isolated from the roots oi Rubia akane grown in Taiwan. Mollugin, a naphthohydroquinone, showed strong inhibition oi arachidonic acid (AA)-induced and collagen-induced platelet aggregation. In contrast, 2-methyl-1,3,6-trihydroxyl-9,10-anthraquinone, xanthopurpurin 3-O-beta-D-glucoside, and xanthopurpurin showed mainly strong inhibition of collagen-induced platelet aggregation.

引用

页码：313 / 316

页数：4

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