HEPATIC TOXICITY OF VITAMIN-A AND SYNTHETIC RETINOIDS

被引：30

作者：

FALLON, MB ^{[1
]}

BOYER, JL ^{[1
]}

机构：

[1] YALE UNIV,SCH MED,LIVER STUDY UNIT,1080 LMP,NEW HAVEN,CT 06510

来源：

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | 1990年 / 5卷 / 03期

关键词：

etretinate; isotretinoin; Key words:; liver; retinol; synthetic retinoids; Vitamin A;

D O I：

10.1111/j.1440-1746.1990.tb01635.x

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Vitamin A and synthetic retinoids have recently been used increasingly in a variety of health related concerns. Hepatic toxicity is an uncommon but serious side‐effect of several Vitamin A derivatives which may lead to cirrhosis. This review will focus on the clinical and pathologic findings of hepatic involvement in chronic hypervitaminosis A and on the evidence concerning the potential hepatotoxicity of currently available synthetic retinoids. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：334 / 342

页数：9

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